Secretive Bio Architecture Lifts Veil On Bio Enzyme Progress

June 13, 2010

Converting algae to biofuel remains an intractable problem even when a company has the resources of a Sapphire Energy and Algenol.

Imagine the challenge facing Bio Architecture Lab. The secretive company confronts the same battle with high costs as it tunes its bioengineered microbe to convert seaweed to ethanol on a commercial scale. But money is nowhere near as plentiful.

Start-up Bio Architecture Lab says it is mid way to 90 percent fuel conversion target.

In a rare discussion of its business, the Berkeley company says it is about half way to its 90 percent fuel conversion target. Confidence is high, says Vineet Rajgarhia, senior vice president of research, who joined the firm in May when it appointed former Shell executive Daniel Trunfio as CEO.

Reaching the target “is doable,” Rajgarhia said at the Cleantech Institute conference at the University of California, Berkeley. “It just needs a little more time.”

That “little more time” is about a year.

The company, spun out of the University of Washington, intends to commercialize its seaweed enzyme for both fuels and chemicals. Up to now, it has been reluctant to offer details about its technology or business plan. But perhaps new management is more willing to communicate.

For example, Rajgarhia says the company’s business plan does not include raising the several hundred million dollars necessary to build its own biorefinery and compete against better-funded competitors. “We’ll be partnering up,” he says.

He also says the company has the breathing room it needs to complete its bioengineering. Rajgarhia estimates the company will require another year to prepare its technology for large-scale deployment. It is no easy task, but since the firm’s goal is to open its Chilean pilot project in 2012, it has the time.

The organization is one of an ambitious few trying to cultivate seaweed, or macro-algae, in shallow coastal waters and turn it into low-cost fuels. In contrast to micro-algae, which floats on the surface, most seaweed, or kelp, attaches itself to the ocean floor and presents a complex harvesting challenge. The effort is likely worth the trouble. Macro-algae can be grown for an estimated $40 a ton, or 4 cents a pound of sugar, far less than corn or sugar cane.  It also uses no agricultural land, fresh water or fertilizer and helps filter ocean waters

Because of the potential economics, its cultivation has drawn the interest of a disparate group of organizations, including Blue Sun Energy of Colorado, Seambiotic of Israel, the Scottish Association for Marine Science and South Korea’s Korea Institute of Industrial Technology.

Bio Architecture Lab drew notice earlier this year when it received a $9 million research grant from the Department of Energy’s ARPA-E. With the award to develop biobutanol, it received matching funds from partner DuPont and last year raised an $8 million series A round with investors X/Seed Capital of Menlo Park, the venture arm of Norways’ Statoil oil company and Austral Capital of Chile. It also received $7 million in economic development money from Chile.

Rajgarhia said a second key challenge Bio Architecture Lab faces is logistical: getting the macro-algae ashore at a cost low enough to produce affordable fuel. The seaweed is fast growing – about 2 feet a day – so volumes add up. And current harvesting techniques are geared toward high-priced food production, so costs are not in line with low-price fuel.

All these tasks, of course, takes money. For companies such as micro-algae developer Sapphire Energy, which has raised more than $100 million, including money from Bill Gates, and Algenol, which promises to fund an $850 million commercial project in Mexico, writing the big check may be possible.

Bio Architecture Lab doesn’t appear to have the same huge outlay in the cards. For the immediate future, at least, “we have a bit of a runway” with the money raised, says Rajgarhia. Long term, it will be interesting to see which business model prospers.


Electricity From Algae: Researchers Collect Electrons From Living Cells

April 14, 2010

Algae cultivation (and lipid extraction) has been the holy grail of the biofuels industry. Now these aquatic organisms – specifically their ability to give off tiny bursts of electrical current – could become the savior of dirty utilities as well.

The vision of huge tubs of algae consuming CO2 and nutrients from wastewater to produce biodiesel and bio-gasoline has drawn scores of scientists to experiment with the notoriously capricious plant.

The fact that algae are difficult to farm hasn’t kept the money from flowing. ExxonMobil last year poured $300 million into joint research with scientist Craig Venter’s Synthetic Genomics. Several months later, Sapphire Energy won $104.5 million in federal loan guarantees and grants from the Agricultural and Energy departments for a demonstration refinery in New Mexico. The Department of Energy earmarked another $44 million a month later in January for nationwide university and other research.

The current harvested so far is tiny, but the potential for bioelectricity from algae is compelling

Now a team of Stanford University researchers is exploring an alternative to the biofuels route. Their work is at an early stage. But its concept is startling: plant-based energy generated without the release of carbon.

The researchers, led by WonHyoung Ryu, now a professor in Korea, pierced each algae cell with a sharp nano-electrode probe made of gold. The probe collected electrons produced during photosynthesis, channeling a small current.

So far, the current from each cell is tiny, just one picoampere. (A trillion cells would be needed to equal the energy stored in a AA battery.) Still, the breakthrough is compelling.

“We believe we are the first to extract electrons out of a living plant cell,” Ryu said in a Stanford release. “This is potentially one of the cleanest energy sources for energy production.”

But it is not without difficulties. Most importantly, the cells died within one hour. Ryu theorizes they may have developed leaks where the probe punctured their membranes. They alternately may have run out of gas after their energy was stolen. The electrons transfer energy from the sun to protein inside the cells.

The research team, which published its work in the journal Nano Letters and included two members from the Carnegie Institution, hopes to change the design of the electrode to lengthen the life of the cells. It also conceives of using larger electrodes and bigger plants with larger chloroplasts, the area of the cell where photosynthesis takes place and water is split into oxygen, protons and electrons. That way, more electrons might be captured.

“We’re still in the scientific stage of the research,” says Ryu. But the potential is great. Electron harvesting has a 20 percent energy efficiency. Plants burned for fuel store only 3 to 6 percent of the sun’s solar energy.

While the work is at an early stage, perhaps it is time to coin the term “bioelectricity.”


Questions Arise About Algae Based Biofuel

January 22, 2010

Algae biofuel is filled with promise. Algae grow fast, consume carbon dioxide and spare the need to fallow cropland from producing food.

Sewage wastewater helps algae cultivation overcome its environmental impact

But doubts have appeared about their contribution to the fight against global warming. Algae require CO2 and fertilizer to grow. However the environmental impact of obtaining these necessary ingredients makes algae cultivation worse for the earth than generating biofuel from switchgrass, canola and corn, according to a study by the University of Virginia, Charlottesville. The study was published this week in the Environmental Science & Technology journal.

Fortunately for algae, all this is turned on its head when sewage plant wastewater is used in place of fertilizer and other sources of CO2, say the researchers from the university’s McIntire School of Commerce.

“Wastewater could be used to offset most of the environmental burdens associated with algae,” an abstract of the study states. It provides the necessary nitrogen and phosphorus.

To its credit, algae generate higher energy yields per acre than planted crops. When wastewater is used in cultivation (purifying the water in the process), commercial trials are clearly are worth the most time and money.


CMEA’s $100 Million Investment Strategy Includes New Materials For Batteries, Wind Towers And Algae Growers

September 30, 2009

CMEA Capital said at last week’s Clinton Global Initiative that it would invest an additional $100 million in alternative energy companies over the next three years.

The commitment, praised by former President Bill Clinton, brings to 50 percent the share of the venture firm’s $400 million seventh fund earmarked for alternative energy and materials investing.

Batteries can transform other industries, such as wind and solar, says Michael Melnick

Batteries can transform other industries, such as wind and solar, says Michael Melnick

“For the first time in history, environmentally-friendly methods for producing energy, like solar and wind power, are becoming inexpensive enough to make mainstream adoption a reality instead of just a pipe dream,” Managing Director Thomas Baruch said in a statement accompanying the announcement.

The San Francisco firm is no stranger to green technology. It invested in 14 alternative energy companies over the past seven years, including battery maker A123 Systems, which launched a successful IPO this month.

Principal Michael Melnick says he and his partners continue to find much to like about investing in new energy technologies. Along with seed-stage startups, CMEA plans to put its money to work in both mid- and late-stage ventures.

At the top of the list are new battery architectures and materials, companies building solar cells and startups developing new materials to make components for wind energy tower. Melnick also says he has an eye open for startups using bio-materials or algae to make high-value chemicals, not simply biofuels.

CMEA doesn’t seem interested in following the herd with its battery strategy. The strategy is not centered on advanced batteries for electric cars, but energy storage devices for solar and wind plants, where energy generation falls off after dark and when the wind doesn’t blow.

The firm announced a new $100 million commitment at the Clinton Global Initiiative

The firm announced a new $100 million commitment at the Clinton Global Initiiative

“We love things like batteries,” he says. “They can transform other industries, for example, wind and solar.” That includes lithium-ion batteries that improve upon those used today. But perhaps more importantly it seeks companies working with electrolytes to replace lithium and other new battery materials.

Melnick says there continues to be huge potential in solar, as well as wind, where new materials are being developed to enhance components in wind towers

In the bio-materials space, Melnick reasons that the first wave of profitable products may be higher priced chemicals and not lower priced fuels. He says he is wary about startups making biofuels, but excited about renewable chemicals.


Algae Biofuel Still About A Decade Away From Competing With Gasoline

September 29, 2009

Biofuel from algae has several key advantages over ethanol typically made from corn or another feedstock. Growing it doesn’t require the use of agricultural land or consume as much water as a field of corn or sugar cane.

But more importantly, it has the potential to return 3 times the energy needed to produce it. Compare that with ethanol’s return of 1.3 times. (Gasoline made from petroleum is a net consumer of energy, returning only eight-tenths of the energy needed to extract and refine it.)

The marine agriculture necessary to grow algae in commercial volumes is still evolving

The marine agriculture necessary to grow algae in commercial volumes is still evolving

These benefits are behind the renewal of interest in algae that has taken place over the past five years. But the hopes of bringing algae biofuel to the market soon may have to wait.

Another three to five years will be needed to master the marine agricultural techniques required to grow algae in the volumes and concentrations necessary to make harvesting biofuel feasible. And it will be seven to 10 years before the fuel is plentiful enough to be a serious substitute for gasoline.

These are the predictions of John Travers, chief executive of AER Limited, an Irish maker of an enzyme technology used to convert raw algae into sugar, protein and oil.

Travers says the main hurdle is in learning the nuances of algae cultivation. Algae require the right amount of sunlight, nutrients and growing conditions. If the organisms grow too quickly, they use up all their food.

“People have been growing corn for a long period of time,” he says. “Marine agricultural knowledge is still evolving.”

Also evolving is the science necessary for converting algae to fuel. During a large-scale August test in a 100-liter container, AER’s enzymes were able to convert algae into sugar, protein and oil with some concentrations from 50 to 80 percent.

“We are ready to go to market next year,” says Travers. Let’s hope some of the growers come along at an equally fast pace.


Algae Scientist With Google Grant Gets Millions From NASA

September 21, 2009

NASA has decided to pony up millions of dollars for a scientist’s schme to grow algae in plastic bags floating in the ocean to harvest biofuel and treat sewage.

The scientist, Jonathan Trent, declined to say exactly how much NASA has earmarked for the project. But he said on Saturday that the last minute funding came after he pitched his plan to big name venture capitalists Vinod Kholsa of Khosla Ventures and Steve Jurvetson of Draper Fisher Jurvetson.

Jonathan Trent pitched his project to Vinod Khosla and Steve Jurvetson

Jonathan Trent pitched his project to VCs Vinod Khosla and Steve Jurvetson

Both had turned him down, though Trent did receive a $62,000 early funding grant from Google.

The ambitious – and still experimental – proposal has a remarkable pair of environment benefits. It has the ability to produce a high quality fuel to replace gasoline and at the same time as cleansing municipal wastewater normally dumped in the ocean. And it does so without transferring farm fields from food production, as other biofuels initiatives require.

Trent, who developed the proposal while working at NASA, says the algae will sequester the greenhouse gas CO2 from the atmosphere while producing a useful by product: agricultural fertilizer. The ocean will regulate the temperature of the algae cultures without using fossil fuel energy and waves will tackle the necessary task of stirring the mixture.

By using plastic bags with a semi-permeable membrane, cleaned water will flow on into the ocean, leaving behind a concentrated mixture of algae and fuel.

Trent says the project isn’t yet financially competitive with the price of oil, but notes it is at an early stage. He says he is working to design the right plastic bag and on a system to protect the bags from storms at sea, perhaps by sinking them below the agitated surface currents.

Because he is using freshwater algae, a project disaster would have little consequence. If the algae were to escape the plastic bag, the salt of the ocean would kill them.

The project is named OMEGA, an acronym for offshore membrane enclosures for growing algae.


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